Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486
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چکیده
منابع مشابه
Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486.
Selective receptor modulators, such as the antiprogestin RU486, are known to exhibit partial agonist activities in a cell-type-dependent manner. Employing an in vitro chromatin transcription system that recapitulates progesterone receptor (PR)-mediated transcription in vivo, we have investigated the molecular basis by which the antiprogestin RU486 regulates transcription in a cell-type-specific...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2002
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.122225699